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- Spires-Jones TL, de Calignon A, Matsui T, Zehr C, Pitstick R, Wu HY, Osetek JD, Jones PB, Bacskai BJ, Feany MB, Carlson GA, Ashe KH, Lewis J, Hyman BT.
In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons.
J Neurosci. 2008 Jan 23;28(4):862-7.
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Steinhilb ML, Dias-Santagata D, Fulga TA, Felch DL, Feany MB.
Tau phosphorylation sites work in concert to promote neurotoxicity in vivo.
Mol Biol Cell. 2007 Dec;18(12):5060-8.
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Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG.
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.
Science. 2007 Jul 27;317(5837):516-9.
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Dufty BM, Warner LR, Hou ST, Jiang SX, Gomez-Isla T, Leenhouts KM, Oxford JT, Feany MB, Masliah E, Rohn TT.
Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation.
Am J Pathol. 2007 May;170(5):1725-38.
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Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB.
Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.
J Neurosci. 2007 Mar 21;27(12):3338-46.
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Steinhilb ML, Dias-Santagata D, Mulkearns EE, Shulman JM, Biernat J, Mandelkow EM, Feany MB.
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila.
J Neurosci Res. 2007 May 1;85(6):1271-8.
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Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB.
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo.
Nat Cell Biol. 2007 Feb;9(2):139-48.
-
Dias-Santagata D, Fulga TA, Duttaroy A, Feany MB.
Oxidative stress mediates tau-induced neurodegeneration in Drosophila.
J Clin Invest. 2007 Jan;117(1):236-45.
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Khurana V, Feany MB.
Connecting cell-cycle activation to neurodegeneration in Drosophila.
Biochim Biophys Acta. 2007 Apr;1772(4):446-56.
- Kontopoulos E, Parvin JD, Feany MB.
Alpha-synuclein acts in the nucleus to inhibit histone acetylation and
promote neurotoxicity.
Hum Mol Genet. 2006 Oct 15;15(20):3012-23.
- Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB.
TOR-mediated cell-cycle activation causes neurodegeneration in
a Drosophila tauopathy model.
Curr Biol. 2006 Feb 7;16(3):230-41.
- Orso G, Martinuzzi A, Rossetto MG, Sartori E, Feany M, Daga A.
Disease-related phenotypes in a Drosophila model of hereditary
spastic paraplegia are ameliorated by treatment with vinblastine.
J Clin Invest. 2005 Nov;115(11):3026-34.
- Khurana V, Fulga TA, Feany MB.
Senseless makes sense for spinocerebellar ataxia-1.
Nat Neurosci. 2005 Nov;8(11):1422-4.
- Myllykangas L, Tyynelä J, Page-McCaw A, Rubin GM, Haltia MJ, Feany
MB.
Cathepsin D-deficient Drosophila recapitulate the key features
of neuronal ceroid lipofuscinoses.
Neurobiol Dis. 2005 Jun-Jul;19(1-2):194-9.
- Chen L, Feany MB.
Alpha-synuclein phosphorylation controls neurotoxicity and inclusion
formation in a Drosophila model of Parkinson disease.
Nat Neurosci. 2005 May;8(5):657-63.
- Colodner KJ, Montana RA, Anthony DC, Folkerth RD, De Girolami U, Feany
MB.
Proliferative potential of human astrocytes.
J Neuropathol Exp Neurol. 2005 Feb;64(2):163-9.
- Feany MB.
New genetic insights into Parkinson's disease.
N Engl J Med. 2004 Nov 4;351(19):1937-40.
- Ghosh S, Feany MB.
Comparison of pathways controlling toxicity in the eye and brain
in Drosophila models of human neurodegenerative diseases.
Hum Mol Genet. 2004 Sep 15;13(18):2011-8.
- Scherzer CR, Feany MB.
Yeast genetics targets lipids in Parkinson's disease.
Trends Genet. 2004 Jul;20(7):273-7.
- Shulman
JM, Feany MB.
Genetic modifiers of tauopathy in Drosophila.
Genetics. 2003 Nov;165(3):1233-42.
- Feany
MB, La Spada AR.
Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases.
Neuron. 2003 Sep 25;40(1):1-2.
- Scherzer
CR, Jensen RV, Gullans SR, Feany MB.
Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease.
Hum Mol Genet. 2003 Oct 1;12(19):2457-66.
Epub 2003 Aug 05.
- Shulman
JM, Shulman LM, Weiner WJ, Feany MB.
From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease.
Curr Opin Neurol. 2003 Aug;16(4):443-9.
- Deleault
NR, Dolph PJ, Feany MB, Cook ME, Nishina K, Harris DA, Supattapone S.
Post-transcriptional suppression of pathogenic prion protein expression in Drosophila neurons.
J
Neurochem. 2003 Jun;85(6):1614-23.
- Feany
MB, Pallanck LJ.
Parkin: a multipurpose neuroprotective agent?
Neuron. 2003 Apr 10;38(1):13-6.
- Greene
JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ.
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants.
Proc Natl Acad
Sci U S A. 2003 Apr 1;100(7):4078-83. Epub 2003 Mar 17.
- Muqit
MM, Feany MB.
Modelling neurodegenerative diseases in Drosophila: a fruitful approach?
Nat Rev Neurosci. 2002 Mar;3(3):237-43.
- Wittmann
CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, Hutton M, Feany MB.
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles.
Science. 2001 Jul 27;293(5530):711-4. Epub 2001 Jun 14.
- Feany
MB, Anthony DC, Frosch MP, Zane W, De Girolami U.
August 2000: Two cases with necrosis and hemorrhage in the putamen and white matter.
Brain Pathol. 2001 Jan;11(1):121-2,
125.
- Feany
MB.
Studying human neurodegenerative diseases in flies and worms.
J Neuropathol Exp Neurol. 2000 Oct;59(10):847-56.
- Feany
MB, Bender WW.
A Drosophila model of Parkinson's disease.
Nature. 2000 Mar 23;404(6776):394-8.
- Feany
MB, Anthony DC, Fletcher CD.
Nerve sheath tumours with hybrid features of neurofibroma and schwannoma: a conceptual challenge.
Histopathology. 1998 May;32(5):405-10.
- Feany
MB, Dickson DW.
Neurodegenerative disorders with extensive tau pathology: a comparative study and review.
Ann Neurol. 1996 Aug;40(2):139-48.
- Feany
MB.
Neuropeptide modulation of learning and memory processes.
Rev Neurosci. 1996 Apr-Jun;7(2):151-64.
- Dickson
DW, Feany MB, Yen SH, Mattiace LA, Davies P.
Cytoskeletal pathology in non-Alzheimer degenerative dementia: new lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration.
J Neural Transm Suppl. 1996;47:31-46.
- Feany
MB, Mattiace LA, Dickson DW.
Neuropathologic overlap of progressive supranuclear palsy, Pick's disease and corticobasal degeneration.
J Neuropathol Exp Neurol. 1996 Jan;55(1):53-67.
- Feany
MB, Dickson DW.
Widespread cytoskeletal pathology characterizes corticobasal degeneration.
Am J Pathol. 1995 Jun;146(6):1388-96.
- Feany
MB, Ksiezak-Reding H, Liu WK, Vincent I, Yen SH, Dickson DW.
Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy.
Acta Neuropathol
(Berl). 1995;90(1):37-43.
- Feany
MB, Quinn WG.
A neuropeptide gene defined by the Drosophila memory mutant amnesiac.
Science. 1995 May 12;268(5212):869-73.
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